Comparing E950 - Acesulfame k vs E421 - Mannitol
Overview
Synonyms
Products
Found in 7,919 products
Found in 571 products
Search rank & volume
Awareness score
Search volume over time
Interest over time for 3 keywords in U.S. during the last 10 years.
Interest over time for 2 keywords in U.S. during the last 10 years.
Popular questions
Is acesulfame potassium bad for you?
For most people, no—acesulfame potassium is approved by major regulators and considered safe at permitted levels; typical diets keep intakes well below the acceptable daily intake.
Why is acesulfame potassium bad for you?
It isn’t generally considered ‘bad’; concerns come from older animal studies or theoretical effects (like on the gut microbiome), but human evidence hasn’t shown harm at normal food-use levels.
Does acesulfame potassium cause cancer?
There’s no convincing evidence that it causes cancer in humans, and FDA, EFSA, and WHO/JECFA evaluations have not found it carcinogenic at permitted intakes.
Is acesulfame potassium bad for kidneys?
No—at typical intakes it’s excreted unchanged in urine and hasn’t been shown to harm kidneys; it adds negligible potassium, though people with severe kidney disease should follow their clinician’s advice.
Is acesulfame potassium safe?
Yes—major regulators (FDA, EFSA, WHO/JECFA) consider it safe within established intake limits, including for people with diabetes and during pregnancy when used as part of a balanced diet.
What is mannitol used for?
In foods, E421 mannitol is used as a low‑calorie sweetener, bulking agent, and humectant/stabilizer (common in sugar‑free gum, candies, and baked goods); it’s also a pharmaceutical excipient. Medically, IV mannitol is an osmotic diuretic to reduce intracranial and intraocular pressure and promote diuresis.
How mannitol works?
As a food ingredient, it’s poorly absorbed so it provides fewer calories and a low glycemic response, with a mild cooling taste. As a medicine, it acts osmotically—filtered by the kidneys and minimally reabsorbed—raising plasma and tubular fluid osmolality to draw water from tissues and increase urine output, lowering brain/eye pressure.
How does mannitol work?
It works osmotically when given IV, increasing blood and renal filtrate osmolality so water moves from tissues into the circulation and then into urine, reducing intracranial and intraocular pressure. In foods, its limited absorption yields a lower-calorie, low‑glycemic sweetening effect.
Is mannitol safe for dogs?
Mannitol isn’t known to be acutely toxic to dogs like xylitol, but ingestion can cause diarrhea and gas, and large amounts may lead to dehydration or electrolyte imbalances. Therapeutic IV mannitol should only be used by a veterinarian; consult your vet especially for dogs with kidney or heart disease.
Is mannitol salt agar selective or differential?
Both: the high salt concentration makes it selective for staphylococci, and mannitol with phenol red makes it differential by turning yellow when mannitol‑fermenting organisms (e.g., many S. aureus) produce acid.