Comparing E627 - Disodium guanylate vs E634 - Calcium 5'-ribonucleotide

Is disodium guanylate bad for you?

No—it's an approved flavor enhancer and considered safe at the tiny amounts used in foods. People with gout or high uric acid may wish to limit it because it's a purine nucleotide.

Is disodium inosinate and guanylate bad for you?

Generally no; the pair (often used as disodium 5'-ribonucleotides) is permitted and considered safe at typical food levels. Those with gout or hyperuricemia may prefer to limit them due to purine content.

What does disodium guanylate do to your body?

It enhances umami/savory taste by activating taste receptors. It’s metabolized like other nucleotides and can break down to uric acid, with no known systemic effects at normal food doses.

Is disodium guanylate msg?

No—it's a different compound (a 5'-nucleotide, E627), though it’s often used together with MSG to intensify umami.

What is disodium inosinate and disodium guanylate?

They are nucleotide flavor enhancers (E631 and E627) used together to amplify savory/umami taste, often alongside MSG. The combination is commonly called disodium 5'-ribonucleotides.