Comparing E450III - Tetrasodium diphosphate vs E450IV - dipotassium dihydrogenpyrophosphate

What is sodium acid pyrophosphate?

You may be thinking of sodium acid pyrophosphate (SAPP, E450i), but this entry covers tetrasodium diphosphate (E450iii), an inorganic phosphate salt used as a sequestrant, stabiliser/emulsifier, humectant and thickener. It helps bind metal ions, control pH and retain moisture in foods like processed meats and seafood.

Is sodium acid pyrophosphate bad for you?

At permitted food levels, tetrasodium diphosphate (E450iii)—a related phosphate—is considered safe by major regulators; EFSA sets a group ADI for phosphates of 40 mg/kg body weight/day (as phosphorus). Very high phosphate or sodium intakes can be a concern for people with kidney disease or on phosphate‑restricted diets.

Is sodium acid pyrophosphate gluten free?

Yes—tetrasodium diphosphate (E450iii) is an inorganic mineral salt and is gluten‑free. As with any ingredient, gluten risk would only come from cross‑contact during manufacturing, not the additive itself.

Is tetrasodium pyrophosphate safe?

Yes—when used within legal limits, tetrasodium diphosphate (E450iii) is permitted and considered safe by regulators (e.g., FDA, EFSA/JECFA), with EFSA’s group ADI for phosphates at 40 mg/kg body weight/day (as phosphorus). People with kidney disease or needing to limit phosphate/sodium should moderate intake.

Is sodium acid pyrophosphate safe?

While you mention SAPP, for the related tetrasodium diphosphate (E450iii) the consensus is that it’s safe at approved levels, under the same phosphate group ADI set by EFSA (40 mg/kg body weight/day as phosphorus). Those with kidney issues or on phosphate‑restricted diets should limit exposure.