Comparing E421 - Mannitol vs E955 - Sucralose
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Found in 571 products
Found in 11,087 products
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Interest over time for 2 keywords in U.S. during the last 10 years.
Interest over time for 2 keywords in U.S. during the last 10 years.
Popular questions
What is mannitol used for?
In foods, E421 mannitol is used as a low‑calorie sweetener, bulking agent, and humectant/stabilizer (common in sugar‑free gum, candies, and baked goods); it’s also a pharmaceutical excipient. Medically, IV mannitol is an osmotic diuretic to reduce intracranial and intraocular pressure and promote diuresis.
How mannitol works?
As a food ingredient, it’s poorly absorbed so it provides fewer calories and a low glycemic response, with a mild cooling taste. As a medicine, it acts osmotically—filtered by the kidneys and minimally reabsorbed—raising plasma and tubular fluid osmolality to draw water from tissues and increase urine output, lowering brain/eye pressure.
How does mannitol work?
It works osmotically when given IV, increasing blood and renal filtrate osmolality so water moves from tissues into the circulation and then into urine, reducing intracranial and intraocular pressure. In foods, its limited absorption yields a lower-calorie, low‑glycemic sweetening effect.
Is mannitol safe for dogs?
Mannitol isn’t known to be acutely toxic to dogs like xylitol, but ingestion can cause diarrhea and gas, and large amounts may lead to dehydration or electrolyte imbalances. Therapeutic IV mannitol should only be used by a veterinarian; consult your vet especially for dogs with kidney or heart disease.
Is mannitol salt agar selective or differential?
Both: the high salt concentration makes it selective for staphylococci, and mannitol with phenol red makes it differential by turning yellow when mannitol‑fermenting organisms (e.g., many S. aureus) produce acid.
Is sucralose bad for you?
For most people, no—sucralose (E955) is approved by major regulators and considered safe within the acceptable daily intake (about 5–15 mg/kg body weight/day, depending on the authority). Some studies note possible effects on the gut microbiome or insulin responses and that very high-heat cooking can degrade sucralose, so use it in moderation and as directed.
Does sucralose raise blood sugar?
On its own, sucralose does not raise blood glucose for most people. Some studies show small insulin or glycemic effects when consumed with carbohydrates, but overall impact is minimal compared with sugar.
Is sucralose bad?
Generally, no—it's regarded as safe at typical intakes under established ADIs. Evidence on long‑term effects on weight or cardiometabolic health is mixed and still being studied.
Is sucralose worse than sugar?
Not typically; sucralose provides sweetness without calories, blood‑sugar spikes, or tooth‑decay risk, whereas sugar adds calories and raises blood glucose. Research on long‑term metabolic effects of non‑nutritive sweeteners is mixed, so choice depends on your goals and tolerance.
Sucralose what is it?
Sucralose (E955) is a noncaloric artificial sweetener made by chlorinating sucrose, about 600 times sweeter than sugar. It's heat‑stable and widely used to sweeten beverages, desserts, and packaged foods.