Comparing E385 - Calcium disodium ethylenediaminetetraacetate vs E578 - calcium gluconate

Synonyms
E385
Calcium disodium ethylenediaminetetraacetate
Calcium disodium EDTA
Calcium disodium ethylene diamine tetra-acetate
calcium disodium EDTA
calcium-dinatrium-EDTA
E-385
E 385
E578
calcium gluconate
Products

Found in 5,291 products

Found in 2 products

Search rank & volume
#1875.1K / mo🇺🇸U.S.
#11217K / mo🇺🇸U.S.
Awareness score

×0.14
under-aware

×355.82
over-aware

Search volume over time

Interest over time for 7 keywords in U.S. during the last 10 years.

Interest over time for 2 keywords in U.S. during the last 10 years.

Popular questions
  1. Is calcium disodium edta harmful?

    When used within approved limits in foods, calcium disodium EDTA (E385) is not considered harmful; regulators have set an acceptable daily intake and typical exposure is well below it. Excessive intake can bind essential minerals and may cause stomach upset, but this is unlikely from normal food use.

  2. Is calcium disodium edta bad for you?

    For most people, no—at permitted food levels it’s considered safe and helps protect flavor and color. Very high doses can chelate essential minerals, but such exposures don’t occur from ordinary foods.

  3. Is calcium disodium edta dairy?

    No—it's a synthetic additive and contains no milk or lactose.

  4. Is calcium disodium edta vegan?

    Yes—it's generally considered vegan because it is chemically synthesized and not derived from animal ingredients.

  5. What is calcium disodium edta in food?

    It’s a sequestrant/antioxidant preservative (E385) that binds trace metals like iron and copper to prevent oxidation, off-flavors, and discoloration in foods such as dressings, mayonnaise, canned vegetables, and beverages.

  1. What is calcium gluconate used for?

    In foods (E578) it acts as a sequestrant and calcium source to improve stability and fortify products; medically it’s used to treat hypocalcemia, protect the heart in severe hyperkalemia, counter magnesium toxicity, and manage hydrofluoric acid exposure.

  2. How does calcium gluconate treat hyperkalemia?

    It doesn’t lower potassium; it stabilizes cardiac cell membranes by increasing extracellular calcium, reducing excitability and the risk of life‑threatening arrhythmias within minutes (effect ~30–60 minutes).

  3. What does calcium gluconate do?

    As a food additive it binds metal ions to prevent quality loss and supplies calcium; as a medicine it replaces calcium, stabilizes the myocardium in hyperkalemia, and treats hypocalcemia and magnesium toxicity.

  4. What is calcium gluconate the antidote for?

    It is an antidote for hydrofluoric acid exposure (topical/systemic) and for magnesium toxicity; it may also be used as an adjunct in calcium channel blocker overdose.

  5. How to administer calcium gluconate injection?

    By healthcare professionals only as slow IV push or infusion (not IM or subcutaneous due to tissue damage); a common adult dose for cardioprotection/hypocalcemia is 10 mL of 10% solution (1 g) over 5–10 minutes with ECG monitoring, repeat as needed. Avoid mixing with bicarbonate or phosphate solutions and monitor for extravasation.