Comparing E341 - Calcium phosphates vs E578 - calcium gluconate
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Popular questions
How does calcium phosphate transfection work?
DNA is mixed with calcium chloride and then added to a phosphate buffer to form fine calcium phosphate–DNA precipitates that attach to cells and are taken up (endocytosis), delivering the genetic material. This is a lab technique and not a food use of E341.
What is mono calcium phosphate?
Monocalcium phosphate [Ca(H2PO4)2], designated E341(i), is an acidic calcium phosphate used as a leavening acid and acidity regulator in baking, and it is relatively water‑soluble.
What is dibasic calcium phosphate?
Dibasic (dicalcium) phosphate [CaHPO4], E341(ii), is a sparingly water‑soluble calcium phosphate used as an anti‑caking agent, buffering agent, and mineral fortificant.
Is calcium phosphate soluble in water?
It depends on the form: monocalcium phosphate is fairly soluble, dicalcium phosphate is sparingly soluble, and tricalcium phosphate is practically insoluble.
What is di calcium phosphate?
Dicalcium phosphate (dibasic calcium phosphate, CaHPO4), E341(ii), is a low‑solubility form used in foods as an anti‑caking agent and as a calcium/phosphate fortificant.
What is calcium gluconate used for?
In foods (E578) it acts as a sequestrant and calcium source to improve stability and fortify products; medically it’s used to treat hypocalcemia, protect the heart in severe hyperkalemia, counter magnesium toxicity, and manage hydrofluoric acid exposure.
How does calcium gluconate treat hyperkalemia?
It doesn’t lower potassium; it stabilizes cardiac cell membranes by increasing extracellular calcium, reducing excitability and the risk of life‑threatening arrhythmias within minutes (effect ~30–60 minutes).
What does calcium gluconate do?
As a food additive it binds metal ions to prevent quality loss and supplies calcium; as a medicine it replaces calcium, stabilizes the myocardium in hyperkalemia, and treats hypocalcemia and magnesium toxicity.
What is calcium gluconate the antidote for?
It is an antidote for hydrofluoric acid exposure (topical/systemic) and for magnesium toxicity; it may also be used as an adjunct in calcium channel blocker overdose.
How to administer calcium gluconate injection?
By healthcare professionals only as slow IV push or infusion (not IM or subcutaneous due to tissue damage); a common adult dose for cardioprotection/hypocalcemia is 10 mL of 10% solution (1 g) over 5–10 minutes with ECG monitoring, repeat as needed. Avoid mixing with bicarbonate or phosphate solutions and monitor for extravasation.