Comparing E330 - Citric acid vs E578 - calcium gluconate
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Found in 95,503 products
Found in 2 products
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Interest over time for 2 keywords in U.S. during the last 10 years.
Interest over time for 2 keywords in U.S. during the last 10 years.
Popular questions
Is citric acid bad for you?
At typical food levels, citric acid (E330) is considered safe by major regulators (GRAS; EFSA/JECFA). Concentrated or frequent acidic exposure can irritate the mouth/stomach or contribute to tooth enamel erosion.
Where does the citric acid cycle occur?
In eukaryotic cells it occurs in the mitochondrial matrix; in bacteria it occurs in the cytosol.
What does citric acid do to your body?
It is a normal intermediate in energy metabolism and is readily metabolized to carbon dioxide and water. Citrate can bind minerals, which may enhance absorption of some and help prevent certain kidney stones by increasing urinary citrate.
Where does citric acid come from?
It occurs naturally in citrus fruits, but most food-grade citric acid is produced by fermenting sugars (e.g., from corn, beet, or cane) with Aspergillus niger.
How is citric acid made?
Industrially, sugars are fermented with Aspergillus niger to produce citric acid, then it is recovered and purified—often by precipitating calcium citrate and converting it back with sulfuric acid or via ion-exchange/crystallization.
What is calcium gluconate used for?
In foods (E578) it acts as a sequestrant and calcium source to improve stability and fortify products; medically it’s used to treat hypocalcemia, protect the heart in severe hyperkalemia, counter magnesium toxicity, and manage hydrofluoric acid exposure.
How does calcium gluconate treat hyperkalemia?
It doesn’t lower potassium; it stabilizes cardiac cell membranes by increasing extracellular calcium, reducing excitability and the risk of life‑threatening arrhythmias within minutes (effect ~30–60 minutes).
What does calcium gluconate do?
As a food additive it binds metal ions to prevent quality loss and supplies calcium; as a medicine it replaces calcium, stabilizes the myocardium in hyperkalemia, and treats hypocalcemia and magnesium toxicity.
What is calcium gluconate the antidote for?
It is an antidote for hydrofluoric acid exposure (topical/systemic) and for magnesium toxicity; it may also be used as an adjunct in calcium channel blocker overdose.
How to administer calcium gluconate injection?
By healthcare professionals only as slow IV push or infusion (not IM or subcutaneous due to tissue damage); a common adult dose for cardioprotection/hypocalcemia is 10 mL of 10% solution (1 g) over 5–10 minutes with ECG monitoring, repeat as needed. Avoid mixing with bicarbonate or phosphate solutions and monitor for extravasation.