Comparing E330 - Citric acid vs E450III - Tetrasodium diphosphate
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Popular questions
Is citric acid bad for you?
At typical food levels, citric acid (E330) is considered safe by major regulators (GRAS; EFSA/JECFA). Concentrated or frequent acidic exposure can irritate the mouth/stomach or contribute to tooth enamel erosion.
Where does the citric acid cycle occur?
In eukaryotic cells it occurs in the mitochondrial matrix; in bacteria it occurs in the cytosol.
What does citric acid do to your body?
It is a normal intermediate in energy metabolism and is readily metabolized to carbon dioxide and water. Citrate can bind minerals, which may enhance absorption of some and help prevent certain kidney stones by increasing urinary citrate.
Where does citric acid come from?
It occurs naturally in citrus fruits, but most food-grade citric acid is produced by fermenting sugars (e.g., from corn, beet, or cane) with Aspergillus niger.
How is citric acid made?
Industrially, sugars are fermented with Aspergillus niger to produce citric acid, then it is recovered and purified—often by precipitating calcium citrate and converting it back with sulfuric acid or via ion-exchange/crystallization.
What is sodium acid pyrophosphate?
You may be thinking of sodium acid pyrophosphate (SAPP, E450i), but this entry covers tetrasodium diphosphate (E450iii), an inorganic phosphate salt used as a sequestrant, stabiliser/emulsifier, humectant and thickener. It helps bind metal ions, control pH and retain moisture in foods like processed meats and seafood.
Is sodium acid pyrophosphate bad for you?
At permitted food levels, tetrasodium diphosphate (E450iii)—a related phosphate—is considered safe by major regulators; EFSA sets a group ADI for phosphates of 40 mg/kg body weight/day (as phosphorus). Very high phosphate or sodium intakes can be a concern for people with kidney disease or on phosphate‑restricted diets.
Is sodium acid pyrophosphate gluten free?
Yes—tetrasodium diphosphate (E450iii) is an inorganic mineral salt and is gluten‑free. As with any ingredient, gluten risk would only come from cross‑contact during manufacturing, not the additive itself.
Is tetrasodium pyrophosphate safe?
Yes—when used within legal limits, tetrasodium diphosphate (E450iii) is permitted and considered safe by regulators (e.g., FDA, EFSA/JECFA), with EFSA’s group ADI for phosphates at 40 mg/kg body weight/day (as phosphorus). People with kidney disease or needing to limit phosphate/sodium should moderate intake.
Is sodium acid pyrophosphate safe?
While you mention SAPP, for the related tetrasodium diphosphate (E450iii) the consensus is that it’s safe at approved levels, under the same phosphate group ADI set by EFSA (40 mg/kg body weight/day as phosphorus). Those with kidney issues or on phosphate‑restricted diets should limit exposure.